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Dec 30, 2025 12:34 pm
Clinical definitions of nephrotic syndrome
| Remission | Urine albumin nil or trace (or proteinuria <4 mg/m2/h) for 3 consecutive early morning specimens. |
| Relapse | Urine albumin 3+ or 4+ (or proteinuria >40 mg/m2/h) for 3 consecutive early morning specimens, after having been in remission previously. |
| Frequent relapses | Two or more relapses in initial 6-month period or more than 3 relapses in any 12 months. |
| Steroid dependence | Two consecutive relapses when on alternate day steroid therapy or within 14 days of its discontinuation. |
| Steroid resistance | Absence of remission despite therapy with daily prednisolone at a dose of 2 mg/kg/d for 4 weeks. |